Definiens Developer XD supports a large variety of biomedical image data formats including DICOM and many propritarian formats of digital slide scanners or cell screening devices.
 

List of Supported Image Formats

Import File Format (Driver) Dimensions File Extension
8-bit transparent PNG   .png
Aperio 2D .svs
Aperio Composite Images 2D .aci
Aperio Annotation Files 2D .xml
Applied Imaging 2D .xml
Analyze AVW 4D  
Analyze 7.5 4D  
Bacus WebSlide 2D .ini
Cellomics c01 2D .dib
DICOM   .dcm, .ima, .ile, none
ESRI Shapefile 2D .shp
Evotec Opera II FLEX 3D .flex
GE Raven FRM 2D .frm
Graphics Interchange Format 2D .gif
Hamamatsu 2D .ndpi
JPEG JFIF 2D .jpg
JPEG 2000 2D .jp2, .j2k
Leica 4D .lif
Microsoft Windows Device Independent Bitmap 2D .bmp
Mirax Slide IO 2D .ini
Olympus dotSlide 2D  
PCO Sensicam 2D .b16
Portable Network Graphics 2D .png
Tagged Image File 2D .tif
Tagged Image File (GeoTIFF) 2D .tif
TissueGnostics 2D .tgnf
X11 Pixmap 2D .xmp
Zeiss ZVI 4D .zvi